View Southwestern
  U.S. Hispanic
  Herbal Remedies

  Education for
  Professionals

  CERT Publications
  Women's Health  
 
C Path
Arizona Health Sciences Center
Center for Education & Research on Therapeutics
     
©2002 Arizona CERT
Google


Search WWW
Search azcert.org

    

 

Browse Drug List


Drugs That Prolong the QT Interval and/or Induce Torsades de Pointes
                                                               Raymond L. Woosley, MD, PhD

Information from the medical literature, the FDA-approved drug labeling and reports submitted to the FDA Adverse Events Reporting System database.

  Browse by clicking on the first letter of the drug's brand or generic name:

A · B · C · D · E · F · G · H · I · J · K · L · M


N · O · P · Q · R · S · T · U · V · W · X · Y · Z
Search by keyword(s):
 
Generic Name Albuterol PubMed Search
Brand Name(s) Proventil®,Ventolin®
Drug Class Bronchodilator
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Alfuzosin PubMed Search
Brand Name(s) Uroxatral®
Drug Class Alpha1-blocker
QT
QT prolongation is mentioned in the FDA-approved labeling as a known action of the drug.
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Amantadine PubMed Search
Brand Name(s) Symmetrel®
Drug Class Dopaminergic/Anti-viral
QT
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Amiodarone PubMed Search
Brand Name(s) Cordarone®,Pacerone®
Drug Class Anti-arrhythmic
QT
QT prolongation is mentioned in the FDA-approved labeling as a known action of the drug.
TdP
The FDA-approved labeling includes mention of cases or a risk of Torsades de Pointes.
Risk Group A drug that is generally accepted by authorities to have a risk of causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments
There are case reports of Torsades de Pointes in the medical literature.
Females>Males,TdP risk regarded as low
   
   



Generic Name Amitriptyline PubMed Search
Brand Name(s) Elavil®
Drug Class Tricyclic Antidepressant
QT
TdP
Risk Group A drug that, in some reports, has been weakly associated with Torsades de Pointes but that, when used in usual dosages, is unlikely to be a risk for Torsades de Pointes.
Comments

   
   



Generic Name Amoxapine PubMed Search
Brand Name(s) Asendin®
Drug Class Tricyclic Antidepressant
QT
TdP
Risk Group A drug that, in some reports, has been weakly associated with Torsades de Pointes but that, when used in usual dosages, is unlikely to be a risk for Torsades de Pointes.
Comments

   
   



Generic Name Amphetamine PubMed Search
Brand Name(s) Adderall® ,Dexadrine®
Drug Class CNS stimulant
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

This includes dextroamphetamine and amphetamine / dextroamphetamine combinations.
   
   



Generic Name Arsenic trioxide PubMed Search
Brand Name(s) Trisenox®
Drug Class Anti-cancer
QT
QT prolongation is mentioned in the labeling as a known action of the drug.
TdP
TdP cases in Literature
Risk Group A drug that is generally accepted by authorities to have a risk of causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments
There are case reports of Torsades de Pointes in the medical literature.
   
   



Generic Name Atomoxetine PubMed Search
Brand Name(s) Strattera®
Drug Class norepinephrine reuptake inhibitor
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Azithromycin PubMed Search
Brand Name(s) Zithromax®
Drug Class Antibiotic
QT
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Chloroquine PubMed Search
Brand Name(s) Arelan®
Drug Class Anti-malarial
QT
TdP
Risk Group A drug that is generally accepted by authorities to have a risk of causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Clomipramine PubMed Search
Brand Name(s) Anafranil®
Drug Class Tricyclic Antidepressant
QT
TdP
Risk Group A drug that, in some reports, has been weakly associated with Torsades de Pointes but that, when used in usual dosages, is unlikely to be a risk for Torsades de Pointes.
Comments

   
   



Generic Name Dolasetron PubMed Search
Brand Name(s) Anzemet®
Drug Class Anti-nausea
QT
QT prolongation is mentioned in the FDA-approved labeling as a known action of the drug.
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Metaproterenol PubMed Search
Brand Name(s) Alupent®,Metaprel®
Drug Class Bronchodilator
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Moxifloxacin PubMed Search
Brand Name(s) Avelox®
Drug Class Antibiotic
QT
QT prolongation is mentioned in the FDA-approved labeling as a known action of the drug.
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Phentermine PubMed Search
Brand Name(s) Adipex®,Fastin®
Drug Class Appetite suppressant
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Phenylpropanolamine PubMed Search
Brand Name(s) Acutrim®,Dexatrim®
Drug Class Decongestant
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



  A note about Brand Names: Drugs are listed with up to 2 common brand names. There are many more brand names for some of the common drugs, such as pseudoephedrine and erythromycin. It is also important to look at the list of active drugs in medicines that contain a combination of drugs such as Zyrtec-D®, which contains pseudoephedrine.
 
 

Arizona Center for Education and Research on Therapeutics
The Critical Path Institute

Tucson, Arizona and Rockville, Maryland

Funded in part by Agency for Healthcare Research and Quality grant 1 U18 HS10385-01

Disclaimer and Waiver
The information presented is intended solely for the purpose of providing general information about health related matters. It is not intended for any other purpose, including, but not limited to, medical or pharmaceutical advice and/or treatment, nor is it intended to substitute for the users' relationships with their own health care/pharmaceutical providers. To that extent, by continued use of this program, the user affirms the understanding of the purpose and releases The Critical Path Institute, The University of Arizona, State of Arizona and Arizona Board of Regents from any claims arising out of his/her use of the website.

Information Center For Consumers Arizona CERT Home For Professionals