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Browse Drug List


Drugs That Prolong the Q-T Interval and/or Induce Torsades de Pointes
Raymond L. Woosley, MD, PhD

Information from the medical literature, the FDA-approved drug labeling and reports submitted to the FDA Adverse Events Reporting System database.

  Browse by clicking on the first letter of the drug's brand or generic name:

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Generic Name Dexmethylphenidate More Info
Brand Name(s) Focalin®
Drug Class CNS stimulant
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Felbamate More Info
Brand Name(s) Felbatrol®
Drug Class Anti-convulsant
QT
TdP
The FDA-approved labeling includes mention of cases or a risk of Torsades de Pointes.
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Fenfluramine More Info
Brand Name(s) Pondimin®
Drug Class Appetite suppressant
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Flecainide More Info
Brand Name(s) Tambocor®
Drug Class Anti-arrhythmic
QT
QT prolongation is mentioned in the FDA-approved labeling as a known action of the drug.
TdP
The FDA-approved labeling includes mention of cases or a risk of Torsades de Pointes.
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments
Association not clear
   
   



Generic Name Fluconazole More Info
Brand Name(s) Diflucan®
Drug Class Anti-fungal
QT
TdP
Risk Group A drug that, in some reports, has been weakly associated with Torsades de Pointes but that, when used in usual dosages, is unlikely to be a risk for Torsades de Pointes.
Comments

   
   



Generic Name Fluoxetine More Info
Brand Name(s) Prozac®,Sarafem®
Drug Class Anti-depressant
QT
QT prolongation is mentioned in the FDA-approved labeling as a known action of the drug.
TdP
The FDA-approved labeling includes mention of cases or a risk of Torsades de Pointes.
Risk Group A drug that, in some reports, has been weakly associated with Torsades de Pointes but that, when used in usual dosages, is unlikely to be a risk for Torsades de Pointes.
Comments
Association not clear
   
   



Generic Name Foscarnet More Info
Brand Name(s) Foscavir®
Drug Class Anti-viral
QT
QT prolongation is mentioned in the FDA-approved labeling as a known action of the drug.
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Fosphenytoin More Info
Brand Name(s) Cerebyx®
Drug Class Anti-convulsant
QT
QT prolongation is mentioned in the FDA-approved labeling as a known action of the drug.
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Gemifloxacin More Info
Brand Name(s) Factive®
Drug Class Antibiotic
QT
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Ofloxacin More Info
Brand Name(s) Floxin®
Drug Class Antibiotic
QT
TdP
Risk Group A drug that may prolong the QT interval but at this time lacks substantial evidence for causing Torsades de Pointes. This drug should be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



Generic Name Phentermine More Info
Brand Name(s) Adipex®,Fastin®
Drug Class Appetite suppressant
QT
TdP
Risk Group A drug to be avoided for use in patients with diagnosed or suspected Congenital Long QT Syndrome.
Comments

   
   



  A note about Brand Names: Drugs are listed with up to 2 common brand names. There are many more brand names for some of the common drugs, such as pseudoephedrine and erythromycin. It is also important to look at the list of active drugs in medicines that contain a combination of drugs such as Zyrtec-D®, which contains pseudoephedrine.
 
 

The University of Arizona Center for Education and Research on Therapeutics
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