» Drug Lists by Risk Groups
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QT Drug Lists by Risk Groups

 

Drugs that Prolong the QT Interval and/or Induce Torsades de Pointes Ventricular Arrhythmia

 

 
 
  Drugs that are generally accepted by the QTdrugs.org Advisory Board of the AzCERT to have a risk of causing torsades de pointes.
 
 
  Drugs that in some reports have been associated with Torsades de Pointes and/or QT prolongation but at this time lack substantial evidence for causing torsades de pointes.
 
 
  Drugs to be avoided for use in patients with diagnosed or suspected congenital long QT syndrome. (Drugs on Lists 1, 2 and 4 should also be avoided by patients with QT syndrome.)
 
 
  Drugs that, in some reports, have been weakly associated with torsades de pointes and/or QT prolongation but that are unlikely to be a risk for Torsades de Pointes when used in usual recommended dosages and in patients without other risk factors (e.g., concomitant QT prolonging drugs, bradycardia, electrolyte disturbances, congenital long QT syndrome, concomitant drugs that inhibit metabolism).
 

Notes about the Lists:
Drugs are listed with up to 2 common brand names.
There are several brand names for some of the common drugs, such as pseudoephedrine and erythromycin. It is also important to look at the list of active drugs in medicines that contain a combination of drugs such as Zyrtec-D®, which contains cetirizine and pseudoephedrine.

Each list includes electronic links to PubMed literature searches so that a comprehensive list of references to current medical literature can be conveniently accessed. The lists are formatted to be viewed online or for printing.

Drugs on the QT Drug Lists are reviewed on an ongoing basis to assure the evidence is still appropriate for their placement on their respective list.  The most recent modification to the lists was done on 03/01/2006.


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