Drugs that in some reports have been associated with Torsades de Pointes and/or QT prolongation but at this time lack substantial evidence for causing Torsades de Pointes.
Alfuzosin Uroxatral® Alpha1-blocker / Benign prostatic hyperplasia
Amantadine Symmetrel® Dopaminergic/Anti-viral / Anti-infective/ Parkinson's Disease
Azithromycin Zithromax® Antibiotic / bacterial infection
Chloral hydrate Noctec® Sedative / sedation/ insomnia
Clozapine Clozaril® Anti-psychotic / schizophrenia
Dolasetron Anzemet® Anti-nausea / nausea, vomiting
Felbamate Felbatrol® Anti-convulsant / seizure
Flecainide Tambocor® Anti-arrhythmic / abnormal heart rhythm
Foscarnet Foscavir® Anti-viral / HIV infection
Fosphenytoin Cerebyx® Anti-convulsant / seizure
Gatifloxacin Tequin® Antibiotic / bacterial infection
Gemifloxacin Factive® Antibiotic / bacterial infection
Granisetron Kytril® Anti-nausea / nausea and vomiting
Indapamide Lozol® Diuretic / stimulate urine & salt loss
Isradipine Dynacirc® Anti-hypertensive / high blood pressure
Levofloxacin Levaquin® Antibiotic / bacterial infection
Lithium Lithobid® Anti-mania / bipolar disorder
Lithium Eskalith® Anti-mania / bipolar disorder
Moexipril/HCTZ Uniretic® Anti-hypertensive / high blood pressure
Moxifloxacin Avelox® Antibiotic / bacterial infection
Nicardipine Cardene® Anti-hypertensive / high blood pressure
Octreotide Sandostatin® Endocrine / acromegaly, carcinoid diarrhea
Ofloxacin Floxin® Antibiotic / bacterial infection
Ondansetron Zofran® Anti-emetic / nausea and vomiting
Quetiapine Seroquel® Anti-psychotic / schizophrenia
Ranolazine Ranexa® Anti-anginal / chronic angina
Risperidone Risperdal® Anti-psychotic / schizophrenia
Roxithromycin* Rulide® Antibiotic / bacterial infection *not available in the United States
Tacrolimus Prograf® Immunosuppressant / Immune suppression
Tamoxifen Nolvadex® Anti-cancer / breast cancer
Telithromycin Ketek® Antibiotic / bacterial infection
Tizanidine Zanaflex® Muscle relaxant /
Vardenafil Levitra® phosphodiesterase inhibitor / vasodilator
Venlafaxine Effexor® Anti-depressant / depression
Voriconazole VFend® Anti-fungal / anti-fungal
Ziprasidone Geodon® Anti-psychotic / schizophrenia
Revised: 12/17/2004

Close Window

Arizona Center for Education and Research on Therapeutics
The Critical Path Institute

Tucson, Arizona and Rockville, Maryland

Funded in part by Agency for Healthcare Research and Quality grant 1 U18 HS10385-01

Disclaimer and Waiver
The information presented is intended solely for the purpose of providing general information about health related matters. It is not intended for any other purpose, including, but not limited to, medical or pharmaceutical advice and/or treatment, nor is it intended to substitute for the users' relationships with their own health care/pharmaceutical providers. To that extent, by continued use of this program, the user affirms the understanding of the purpose and releases The Critical Path Institute, The University of Arizona, State of Arizona and Arizona Board of Regents from any claims arising out of his/her use of the website.


Risk Group 4 Risk Group 3 Risk Group 1