Drugs that in some reports have been associated with torsades de pointes and/or QT prolongation but at this time lack substantial evidence for causing torsades de pointes.
Dolasetron Anzemet® Anti-nausea / nausea, vomiting
Moxifloxacin Avelox® Antibiotic / bacterial infection
Nicardipine Cardene® Anti-hypertensive / high blood pressure
Fosphenytoin Cerebyx® Anti-convulsant / seizure
Clozapine Clozaril® Anti-psychotic / schizophrenia
Isradipine Dynacirc® Anti-hypertensive / high blood pressure
Venlafaxine Effexor® Anti-depressant / depression
Lithium Eskalith® Anti-mania / bipolar disorder
Gemifloxacin Factive® Antibiotic / bacterial infection
Felbamate Felbatrol® Anti-convulsant / seizure
Ofloxacin Floxin® Antibiotic / bacterial infection
Foscarnet Foscavir® Anti-viral / HIV infection
Ziprasidone Geodon® Anti-psychotic / schizophrenia
Telithromycin Ketek® Antibiotic / bacterial infection
Granisetron Kytril® Anti-nausea / nausea and vomiting
Levofloxacin Levaquin® Antibiotic / bacterial infection
Vardenafil Levitra® phosphodiesterase inhibitor / vasodilator
Lithium Lithobid® Anti-mania / bipolar disorder
Indapamide Lozol® Diuretic / stimulate urine & salt loss
Chloral hydrate Noctec® Sedative / sedation/ insomnia
Tamoxifen Nolvadex® Anti-cancer / breast cancer
Tacrolimus Prograf® Immunosuppressant / Immune suppression
Ranolazine Ranexa® Anti-anginal / chronic angina
Risperidone Risperdal® Anti-psychotic / schizophrenia
Roxithromycin* Rulide® Antibiotic / bacterial infection *not available in the United States
Octreotide Sandostatin® Endocrine / acromegaly, carcinoid diarrhea
Quetiapine Seroquel® Anti-psychotic / schizophrenia
Amantadine Symmetrel® Dopaminergic/Anti-viral / Anti-infective/ Parkinson's Disease
Flecainide Tambocor® Anti-arrhythmic / abnormal heart rhythm
Gatifloxacin Tequin® Antibiotic / bacterial infection
Moexipril/HCTZ Uniretic® Anti-hypertensive / high blood pressure
Alfuzosin Uroxatral® Alpha1-blocker / Benign prostatic hyperplasia
Voriconazole VFend® Anti-fungal / anti-fungal
Tizanidine Zanaflex® Muscle relaxant /
Azithromycin Zithromax® Antibiotic / bacterial infection
Ondansetron Zofran® Anti-emetic / nausea and vomiting
Revised: 03/01/2006

Source: www.QTdrugs.org

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Drugs on the QT Drug Lists are reviewed on an ongoing basis to assure the evidence is still appropriate for their placement on their respective list.


Arizona Center for Education and Research on Therapeutics
The Critical Path Institute

Tucson, Arizona and Rockville, Maryland

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