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Center for Education & Research on Therapeutics
     
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Pub Med Search: Brand Name & Generic

Drugs That Prolong the QT Interval and/or Induce Torsades de Pointes.


Click on a drug name to perform a PubMed literature search for that drug.
Click "List" for a description of the Drug Risk Groups.

  Generic Name Brand Name Class/Clinical Use List
Albuterol Ventolin® Bronchodilator / Asthma 3
Albuterol Proventil® Bronchodilator / Asthma 3
Alfuzosin Uroxatral® Alpha1-blocker / Benign prostatic hyperplasia 2
Amantadine Symmetrel® Dopaminergic/Anti-viral / Anti-infective/ Parkinson's Disease 2
Amiodarone Pacerone® Anti-arrhythmic / abnormal heart rhythm 1
Amiodarone Cordarone® Anti-arrhythmic / abnormal heart rhythm 1
Amitriptyline Elavil® Tricyclic Antidepressant / depression 4
Amoxapine Asendin® Tricyclic Antidepressant / depression 4
Amphetamine Adderall® CNS stimulant / ADHD 3
Amphetamine Dexadrine® CNS stimulant / ADHD 3
Arsenic trioxide Trisenox® Anti-cancer / Leukemia 1
Atomoxetine Strattera® norepinephrine reuptake inhibitor / ADHD 3
Azithromycin Zithromax® Antibiotic / bacterial infection 2
Bepridil Vascor® Anti-anginal / heart pain 1
Chloral hydrate Noctec® Sedative / sedation/ insomnia 2
Chloroquine Arelan® Anti-malarial / malaria infection 1
Chlorpromazine Thorazine® Anti-psychotic/ Anti-emetic / schizophrenia/ nausea 1
Ciprofloxacin Cipro® Antibiotic / bacterial infection 4
Cisapride Propulsid® GI stimulant / heartburn 1
Citalopram Celexa® Anti-depressant / depression 4
Clarithromycin Biaxin® Antibiotic / bacterial infection 1
Clomipramine Anafranil® Tricyclic Antidepressant / depression 4
Clozapine Clozaril® Anti-psychotic / schizophrenia 2
Cocaine Cocaine Local anesthetic / 3
Desipramine Pertofrane® Tricyclic Antidepressant / depression 4
Dexmethylphenidate Focalin® CNS stimulant / ADHD 3
Disopyramide Norpace® Anti-arrhythmic / abnormal heart rhythm 1
Dobutamine Dobutrex® Catecholamine / heart failure and shock 3
Dofetilide Tikosyn® Anti-arrhythmic / abnormal heart rhythm 1
Dolasetron Anzemet® Anti-nausea / nausea, vomiting 2
Domperidone* Motilium® Anti-nausea / nausea 1
Dopamine Intropine® Anti-arrhythmic / abnormal heart rhythm 3
Doxepin Sinequan® Tricyclic Antidepressant / depression 4
Droperidol Inapsine® Sedative;Anti-nausea / anesthesia adjunct, nausea 1
Ephedrine Broncholate® Bronchodilator, decongestant / Allergies, sinusitis, asthma 3
Ephedrine Rynatuss® Bronchodilator, decongestant / Allergies, sinusitis, asthma 3
Epinephrine Primatene® catecholamine, vasoconstrictor / anaphylaxis, allergic reactions 3
Epinephrine Bronkaid® catecholamine, vasoconstrictor / anaphylaxis, allergic reactions 3
Erythromycin Erythrocin® Antibiotic;GI stimulant / bacterial infection; increase GI motility 1
Erythromycin E.E.S.® Antibiotic;GI stimulant / bacterial infection; increase GI motility 1
Felbamate Felbatrol® Anti-convulsant / seizure 2
Fenfluramine Pondimin® Appetite suppressant / dieting, weight loss 3
Flecainide Tambocor® Anti-arrhythmic / abnormal heart rhythm 2
Fluconazole Diflucan® Anti-fungal / fungal infection 4
Fluoxetine Sarafem® Anti-depressant / depression 4
Fluoxetine Prozac® Anti-depressant / depression 4
Foscarnet Foscavir® Anti-viral / HIV infection 2
Fosphenytoin Cerebyx® Anti-convulsant / seizure 2
Galantamine Reminyl® Cholinesterase inhibitor / Dementia, Alzheimer's 4
Gatifloxacin Tequin® Antibiotic / bacterial infection 2
Gemifloxacin Factive® Antibiotic / bacterial infection 2
Granisetron Kytril® Anti-nausea / nausea and vomiting 2
Halofantrine Halfan® Anti-malarial / malaria infection 1
Haloperidol Haldol® Anti-psychotic / schizophrenia, agitation 1
Ibutilide Corvert® Anti-arrhythmic / abnormal heart rhythm 1
Imipramine Norfranil® Tricyclic Antidepressant / depression 4
Indapamide Lozol® Diuretic / stimulate urine & salt loss 2
Isoproterenol Isupres® Catecholamine / allergic reaction 3
Isoproterenol Medihaler-Iso® Catecholamine / allergic reaction 3
Isradipine Dynacirc® Anti-hypertensive / high blood pressure 2
Itraconazole Sporanox® Anti-fungal / fungal infection 4
Ketoconazole Nizoral® Anti-fungal / fungal infection 4
Levalbuterol Xopenex® Bronchodilator / asthma 3
Levofloxacin Levaquin® Antibiotic / bacterial infection 2
Levomethadyl Orlaam® Opiate agonist / pain control, narcotic dependence 1
Lithium Eskalith® Anti-mania / bipolar disorder 2
Lithium Lithobid® Anti-mania / bipolar disorder 2
Mesoridazine Serentil® Anti-psychotic / schizophrenia 1
Metaproterenol Alupent® Bronchodilator / asthma 3
Metaproterenol Metaprel® Bronchodilator / asthma 3
Methadone Dolophine® Opiate agonist / pain control, narcotic dependence 1
Methadone Methadose® Opiate agonist / pain control, narcotic dependence 1
Methylphenidate Ritalin® CNS stimulant / ADHD 3
Methylphenidate Concerta® CNS stimulant / ADHD 3
Mexiletine Mexitil® Anti-arrhythmic / Abnormal heart rhythm 4
Midodrine ProAmatine® Vasoconstrictor / low blood pressure, fainting 3
Moexipril/HCTZ Uniretic® Anti-hypertensive / high blood pressure 2
Moxifloxacin Avelox® Antibiotic / bacterial infection 2
Nicardipine Cardene® Anti-hypertensive / high blood pressure 2
Norepinephrine Levophed® Vasconstrictor, Inotrope / shock, low blood pressure 3
Nortriptyline Pamelor® Tricyclic Antidepressant / depression 4
Octreotide Sandostatin® Endocrine / acromegaly, carcinoid diarrhea 2
Ofloxacin Floxin® Antibiotic / bacterial infection 2
Ondansetron Zofran® Anti-emetic / nausea and vomiting 2
Paroxetine Paxil® Anti-depressant / depression 4
Pentamidine NebuPent® Anti-infective / pneumocystis pneumonia 1
Pentamidine Pentam® Anti-infective / pneumocystis pneumonia 1
Phentermine Fastin® Appetite suppressant / dieting, weight loss 3
Phentermine Adipex® Appetite suppressant / dieting, weight loss 3
Phenylephrine Neosynephrine® Vasoconstrictor, decongestant / low blood pressure, allergies, sinusitis, asthma 3
Phenylpropanolamine Acutrim® Decongestant / allergies, sinusitis, asthma 3
Phenylpropanolamine Dexatrim® Decongestant / allergies, sinusitis, asthma 3
Pimozide Orap® Anti-psychotic / Tourette's tics 1
Procainamide Pronestyl® Anti-arrhythmic / abnormal heart rhythm 1
Procainamide Procan® Anti-arrhythmic / abnormal heart rhythm 1
Protriptyline Vivactil® Tricyclic Antidepressant / depression 4
Pseudoephedrine PediaCare® Decongestant / allergies, sinusitis, asthma 3
Pseudoephedrine Sudafed® Decongestant / allergies, sinusitis, asthma 3
Quetiapine Seroquel® Anti-psychotic / schizophrenia 2
Quinidine Quinaglute® Anti-arrhythmic / abnormal heart rhythm 1
Quinidine Cardioquin® Anti-arrhythmic / abnormal heart rhythm 1
Ranolazine Ranexa® Anti-anginal / chronic angina 2
Risperidone Risperdal® Anti-psychotic / schizophrenia 2
Ritodrine Yutopar® Uterine relaxant / prevent premature labor 3
Roxithromycin* Rulide® Antibiotic / bacterial infection 2
Salmeterol Serevent® Sympathomimetic / asthma, COPD 3
Sertraline Zoloft® Anti-depressant / depression 4
Sibutramine Meridia® Appetitie suppressant / dieting, weight loss 3
Solifenacin VESIcare® muscarinic receptor anatagonist / treatment of overactive bladder 4
Sotalol Betapace® Anti-arrhythmic / abnormal heart rhythm 1
Sparfloxacin Zagam® Antibiotic / bacterial infection 1
Tacrolimus Prograf® Immunosuppressant / Immune suppression 2
Tamoxifen Nolvadex® Anti-cancer / breast cancer 2
Telithromycin Ketek® Antibiotic / bacterial infection 2
Terbutaline Brethine® Bronchodilator / asthma 3
Thioridazine Mellaril® Anti-psychotic / schizophrenia 1
Tizanidine Zanaflex® Muscle relaxant / 2
Tolterodine Detrol® Bladder Antispasmodic / 3
Tolterodine Detrol LA® Bladder Antispasmodic / 3
Trimethoprim-Sulfa Sulfa® Antibiotic / bacterial infection 4
Trimethoprim-Sulfa Bactrim® Antibiotic / bacterial infection 4
Trimipramine Surmontil® Tricyclic Antidepressant / depression 4
Vardenafil Levitra® phosphodiesterase inhibitor / vasodilator 2
Venlafaxine Effexor® Anti-depressant / depression 2
Voriconazole VFend® Anti-fungal / anti-fungal 2
Ziprasidone Geodon® Anti-psychotic / schizophrenia 2

 

 
A note about Brand Names: Drugs are listed with up to 2 common brand names. There are several brand names for some of the common drugs, such as pseudoephedrine and erythromycin. It is also important to look at the list of active drugs in medicines that contain a combination of drugs such as Zyrtec-D®, which contains cetirizine and pseudoephedrine.
 

Revised: 03/01/2006

Drugs on the QT Drug Lists are reviewed on an ongoing basis to assure the evidence is still appropriate for their placement on their respective list.


Arizona Center for Education and Research on Therapeutics
The Critical Path Institute

Tucson, Arizona and Rockville, Maryland

Funded in part by Agency for Healthcare Research and Quality grant 1 U18 HS10385-01

Disclaimer and Waiver
The information presented is intended solely for the purpose of providing general information about health related matters. It is not intended for any other purpose, including, but not limited to, medical or pharmaceutical advice and/or treatment, nor is it intended to substitute for the users' relationships with their own health care/pharmaceutical providers. To that extent, by continued use of this program, the user affirms the understanding of the purpose and releases The Critical Path Institute, The University of Arizona, State of Arizona and Arizona Board of Regents from any claims arising out of his/her use of the website.

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