Centers for Education &
Research on Therapeutics™
Johnson JA et al. Arch Intern Med 1995;155(18):1949–1956
Leape LL et al. N Engl J Med 1991;324(6):377–384
Classen DC et al. JAMA 1997;277(4):301–306
Costs Associated with ADRs
§$136 BILLION yearly
§Greater than total costs of cardiovascular or diabetic care
§ADRs cause 1 out of 5 injuries or deaths per year to hospitalized patients
§Mean length of stay, cost and mortality for ADR patients are DOUBLE that for control patients