Centers for Education &
Research on Therapeutics™
*These programs are not endorsed by the FDA
Drug-Drug Interactions:
 A Stepwise Approach
§1. Take a medication history (AVOID mistakes)
 2. Remember high risk patients
•Any patient taking 2 medications
•Anticonvulsants, antibiotics, digoxin,
 warfarin, amiodarone, etc
 3. Check pocket reference
 4. Consult pharmacists/drug info specialists
 5. Check up-to-date computer program
•Medical Letter Drug Interaction Program*
•Clinical pharmacology (gsm.com)*
•www.epocrates.com*