§ 39 y.o. female with 2-day Hx of intermittent syncope § Rx with terfenadine 60 mg bid and cefaclor 250 mg tid ´ 10 d § Self-medicated with ketoconazole 200 mg bid for vaginal candidiasis § Palpitations, syncope, torsades de pointes (QTc 655 msec)