||Larrea tridentata (Sessé & Moc. ex DC.) Coville
||Chaparral, creosote bush, gobernadora, greasewood, hediondilla
|Studies on Diabetes
||A pure compound isolated from larrea resulted in an 8 mmol/lt decrease in blood sugar in male mice following oral administration (Luo 1998).
||Folk uses include cancer treatment, dermatitis (topical), rheumatic disorders and upper respiratory infection (Johnson 2002).
|Formulations used by Informants
||Hot infusion, ointment.
||Nordihydroguaiaretic acid (NDGA-a phenolic constituent and potent anti-oxidant), flavanoids, volatile oils, wax, esters, and triterpenes (Kay 1996).
|Potential Adverse Effects
||Hepatotoxicity has been associated with "chapparal" tea. The American Herbal Products Association(AHPA) and the FDA requested removal from health food stores; no hepatotoxic properties were found. AHPA recinded the ban (Kay 1996).
|Potential Medication Interactions
||No significant interactions were found.